| Item Type | Name |
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Academic Article
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Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth.
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Academic Article
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STAT3 mediates resistance to MEK inhibitor through microRNA miR-17.
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Academic Article
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Targeting different types of human meningioma and glioma cells using a novel adenoviral vector expressing GFP-TRAIL fusion protein from hTERT promoter.
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Academic Article
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Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo.
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Concept
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Protein Structure, Tertiary
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Concept
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Adenovirus E4 Proteins
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Concept
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Mitogen-Activated Protein Kinase 8
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Concept
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Protein-Tyrosine Kinases
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Concept
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Adenovirus E1A Proteins
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Concept
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Membrane Proteins
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Concept
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Adenovirus E1 Proteins
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Concept
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DNA-Binding Proteins
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Concept
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Protein Folding
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Concept
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Glutathione Reductase
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Concept
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Heat-Shock Proteins
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Concept
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Unfolded Protein Response
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Concept
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Adenovirus Early Proteins
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Concept
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Tumor Suppressor Protein p53
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Concept
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Mitogen-Activated Protein Kinases
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Concept
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Herpes Simplex Virus Protein Vmw65
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Concept
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Protein Biosynthesis
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Concept
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Luminescent Proteins
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Concept
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Mitogen-Activated Protein Kinase 9
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Concept
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Protein Kinase Inhibitors
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Concept
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Carrier Proteins
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Concept
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Proto-Oncogene Proteins c-bcl-2
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Concept
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Cell Cycle Proteins
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Concept
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Mitochondrial Proteins
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Concept
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Viral Structural Proteins
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Concept
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Insulin-Like Growth Factor Binding Protein 2
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Concept
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Receptor Protein-Tyrosine Kinases
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Concept
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Green Fluorescent Proteins
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Concept
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ras Proteins
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Concept
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Recombinant Fusion Proteins
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Concept
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Inhibitor of Apoptosis Proteins
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Concept
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Capsid Proteins
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Concept
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Fungal Proteins
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Concept
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Saccharomyces cerevisiae Proteins
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Concept
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Mitogen-Activated Protein Kinase Kinases
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Concept
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HSP70 Heat-Shock Proteins
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Concept
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Disulfides
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Concept
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Iron-Sulfur Proteins
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Concept
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Nuclear Proteins
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Concept
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Recombinant Proteins
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Concept
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Protein Kinases
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Concept
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bcl-2-Associated X Protein
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Concept
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Neoplasm Proteins
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Concept
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Insulin-Like Growth Factor Binding Proteins
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Concept
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JNK Mitogen-Activated Protein Kinases
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Concept
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Focal Adhesion Protein-Tyrosine Kinases
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Concept
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Adenovirus E3 Proteins
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Concept
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bcl-X Protein
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Concept
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Adenovirus E2 Proteins
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Concept
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AMP-Activated Protein Kinases
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Concept
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Intracellular Signaling Peptides and Proteins
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Concept
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BH3 Interacting Domain Death Agonist Protein
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Concept
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Kv Channel-Interacting Proteins
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Concept
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CASP8 and FADD-Like Apoptosis Regulating Protein
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Concept
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Proto-Oncogene Proteins c-mdm2
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Concept
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Proto-Oncogene Proteins c-met
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Concept
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Arabidopsis Proteins
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Concept
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Adaptor Proteins, Vesicular Transport
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Concept
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Insulin-Like Growth Factor Binding Protein 6
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Concept
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Apoptosis Regulatory Proteins
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Concept
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Proto-Oncogene Proteins
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Concept
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bcl-2 Homologous Antagonist-Killer Protein
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Concept
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Tumor Suppressor Proteins
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Concept
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RNA-Binding Proteins
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Concept
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Protein Array Analysis
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Concept
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Viral Proteins
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Concept
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Iron-Regulatory Proteins
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Concept
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Repressor Proteins
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Concept
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Protein Kinase C-delta
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Concept
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Proto-Oncogene Proteins c-akt
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Concept
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Proteins
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Concept
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Thioredoxin-Disulfide Reductase
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Academic Article
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Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene.
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Academic Article
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Identification of tissue- and cancer-selective promoters for the introduction of genes into human ovarian cancer cells.
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Academic Article
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Intercellular trafficking of VP22-GFP fusion proteins is not observed in cultured mammalian cells.
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Academic Article
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Reduced toxicity, attenuated immunogenicity and efficient mediation of human p53 gene expression in vivo by an adenovirus vector with deleted E1-E3 and inactivated E4 by GAL4-TATA promoter replacement.
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Academic Article
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A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax.
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Academic Article
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Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells.
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Academic Article
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Adenovirus-mediated Bak gene transfer induces apoptosis in mesothelioma cell lines.
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Academic Article
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Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death.
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Academic Article
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Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis.
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Academic Article
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Molecular therapy for peritoneal dissemination of xenotransplanted human MKN-45 gastric cancer cells with adenovirus mediated Bax gene transfer.
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Academic Article
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Induction of S-phase arrest and p21 overexpression by a small molecule 2[[3-(2,3-dichlorophenoxy)propyl] amino]ethanol in correlation with activation of ERK.
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Academic Article
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Oncolytic virotherapy for cancer treatment: challenges and solutions.
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Academic Article
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Combination effect of oncolytic adenovirotherapy and TRAIL gene therapy in syngeneic murine breast cancer models.
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Academic Article
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[Activity of the TNF-related apoptosis-inducing ligand gene expressed from the hTERT promoter on colon cancer cell line HT-29].
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Academic Article
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JNK-deficiency enhanced oncolytic vaccinia virus replication and blocked activation of double-stranded RNA-dependent protein kinase.
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Academic Article
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Treatment of patient tumor-derived colon cancer xenografts by a TRAIL gene-armed oncolytic adenovirus.
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Academic Article
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Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type. P53 (Ad-p53).
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Academic Article
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A role for mitochondrial Bak in apoptotic response to anticancer drugs.
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Academic Article
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Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells.
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Academic Article
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Tumor necrosis factor-related apoptosis-inducing ligand gene on human colorectal cancer cell line HT29.
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Academic Article
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GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells.
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Academic Article
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Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells.
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Academic Article
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Suppression of pancreatic tumor growth in the liver by systemic administration of the TRAIL gene driven by the hTERT promoter.
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Academic Article
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Mechanisms of resistance to TRAIL-induced apoptosis in cancer.
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Academic Article
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JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells.
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Academic Article
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a-Catenin inhibits glioma cell migration, invasion, and proliferation by suppression of ?-catenin transactivation.
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Academic Article
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Lack of persistence of E1- recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs.
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Academic Article
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Diminishing adenovirus gene expression and viral replication by promoter replacement.
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Academic Article
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Evaluation of GAL4/TATA in vivo. Induction of transgene expression by adenovirally mediated gene codelivery.
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Academic Article
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A rapid, sensitive, and nonradioactive method for assay of FHIT Ap3A hydrolase activity by fluorescence thin-layer chromatographic image analysis.
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Academic Article
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Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression.
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Academic Article
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Adenoviral Bak overexpression mediates caspase-dependent tumor killing.
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Academic Article
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Insulin-like growth factor binding protein-6 inhibits the growth of human bronchial epithelial cells and increases in abundance with all-trans-retinoic acid treatment.
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Academic Article
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Augmenting transgene expression from carcinoembryonic antigen (CEA) promoter via a GAL4 gene regulatory system.
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Academic Article
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Significant augmentation of pro-apoptotic gene therapy by pharmacologic bcl-xl down-regulation in mesothelioma.
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Academic Article
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Targeting HER-2/neu-overexpressing breast cancer cells by an antisense iron responsive element-directed gene expression.
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Academic Article
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hTERT promoter induces tumor-specific Bax gene expression and cell killing in syngenic mouse tumor model and prevents systemic toxicity.
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Academic Article
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Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line.
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Academic Article
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Combined TRAIL and Bax gene therapy prolonged survival in mice with ovarian cancer xenograft.
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Academic Article
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TRAIL-beta and TRAIL-gamma: two novel splice variants of the human TNF-related apoptosis-inducing ligand (TRAIL) without apoptotic potential.
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Academic Article
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Anti-liver cancer activity of TNF-related apoptosis-inducing ligand gene and its bystander effects.
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Academic Article
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[Adenoviral vector expressing the TRAIL gene driven by the hTERT promoter].
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Academic Article
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Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells.
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Academic Article
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Oncolysis and suppression of tumor growth by a GFP-expressing oncolytic adenovirus controlled by an hTERT and CMV hybrid promoter.
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Academic Article
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Enhancing anti-cancer virotherapy with heat-shock protein-mediated immune response.
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Academic Article
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Coxsackie-adenovirus receptor as a novel marker of stem cells in treatment-resistant non-small cell lung cancer.
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Academic Article
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Prognostic significance of combinations of RNA-dependent protein kinase and EphA2 biomarkers for NSCLC.
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Academic Article
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Insulin-like growth factor binding proteins increase intracellular calcium levels in two different cell lines.
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Academic Article
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IGFBP2/FAK pathway is causally associated with dasatinib resistance in non-small cell lung cancer cells.
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Academic Article
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Development of synthetic lethality anticancer therapeutics.
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Academic Article
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Antitumor effect of adenovirus-mediated Bax gene transfer on p53-sensitive and p53-resistant cancer lines.
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Academic Article
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Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers.
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Academic Article
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Isolated limb perfusion: a novel delivery system for wild-type p53 and fiber-modified oncolytic adenoviruses to extremity sarcoma.
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Academic Article
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KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancer.
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Academic Article
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Antitumor activity of a novel oncrasin analogue is mediated by JNK activation and STAT3 inhibition.
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Academic Article
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The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent manner.
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Academic Article
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Insulin-like growth factor binding protein-2 level is increased in blood of lung cancer patients and associated with poor survival.
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Academic Article
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RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer.
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Academic Article
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Predictive biomarkers in precision medicine and drug development against lung cancer.
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Academic Article
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RAS signaling and anti-RAS therapy: lessons learned from genetically engineered mouse models, human cancer cells, and patient-related studies.
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Academic Article
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RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer
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Academic Article
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Accumulation of RNA-dependent protein kinase (PKR) in the nuclei of lung cancer cells mediates radiation resistance
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Academic Article
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Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells.
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Academic Article
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Accumulation of RNA-dependent protein kinase (PKR) in the nuclei of lung cancer cells mediates radiation resistance.
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Academic Article
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TUSC2(FUS1)-erlotinib Induced Vulnerabilities in Epidermal Growth Factor Receptor(EGFR) Wildtype Non-small Cell Lung Cancer(NSCLC) Targeted by the Repurposed Drug Auranofin.
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Academic Article
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B-Cell Lymphoma Patient-Derived Xenograft Models Enable Drug Discovery and Are a Platform for Personalized Therapy.
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Academic Article
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HER2 Confers Resistance to Foretinib Inhibition of MET-Amplified Esophageal Adenocarcinoma Cells.
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Academic Article
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Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis.
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Academic Article
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Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer.
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Academic Article
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Targeting PKCd as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer.
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Academic Article
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Non-canonical cMet regulation by vimentin mediates Plk1 inhibitor-induced apoptosis.
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Concept
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Kelch-Like ECH-Associated Protein 1
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Concept
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Poly-ADP-Ribose Binding Proteins
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Concept
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Coxsackie and Adenovirus Receptor-Like Membrane Protein
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Concept
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Ataxia Telangiectasia Mutated Proteins
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Academic Article
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Glutathione reductase (GSR) gene deletion and chromosome 8 aneuploidy in primary lung cancers detected by fluorescence in situ hybridization.
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Academic Article
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Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells.
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Academic Article
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Repurposing auranofin to treat TP53-mutated or PTEN-deleted refractory B-cell lymphoma.
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Academic Article
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Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer.
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Academic Article
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The laboratory's role in combating COVID-19.
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Academic Article
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Concurrent use of aspirin with osimertinib is associated with improved survival in advanced EGFR-mutant non-small cell lung cancer.
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Academic Article
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PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis.
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Academic Article
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mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation.
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Academic Article
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Combined MEK/MDM2 inhibition demonstrates antitumor efficacy in TP53 wild-type thyroid and colorectal cancers with MAPK alterations.
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Academic Article
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3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib.
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